Recall

A newborn is cyanotic shortly after birth. Oxygen therapy does not improve saturation.What is the most likely diagnosis?

A. Respiratory distress syndrome

B. Tetralogy of Fallot

C. Transposition of the great arteries

D. Patent ductus arteriosus

E. Ventricular septal defect

✅ Answer: C. Transposition of the great arteries

Explanation: Severe cyanosis not responding to oxygen suggests a duct-dependent congenital heart lesion like TGA.