MRCPCH exam preparation guide
MRCPCH exam preparation guide Recall: 3 yrs old patient has chicken pox, presented with disseminated erythema, fever, tachycardia 180 bpm, BP 70/40 mm Hg, decreased UOP, CRT < 1 sec, pnt is already on ceftriaxone. What will you add? Clindamycin Vancomycin Benzylpenicillin Rifampicin gentamicin Explanation This is a clinical scenario that suggests severe sepsis or…
MRCPCH exam preparation guide
Recall: 3 yrs old patient has chicken pox, presented with disseminated erythema, fever, tachycardia 180 bpm, BP 70/40 mm Hg, decreased UOP, CRT < 1 sec, pnt is already on ceftriaxone. What will you add?
- Clindamycin
- Vancomycin
- Benzylpenicillin
- Rifampicin
- gentamicin
Explanation
This is a clinical scenario that suggests severe sepsis or toxic shock syndrome in a 3-year-old with chickenpox (varicella) and a presentation of disseminated erythema, fever, hypotension (shock), tachycardia, and oliguria (reduced urine output).
In this case, the child is already on ceftriaxone (which covers a broad range of infections including many Gram-positive and Gram-negative bacteria), but given the severe presentation, we need to consider adding coverage for MRSA (Methicillin-resistant Staphylococcus aureus) or other resistant organisms that could be complicating the case, like Toxic Shock Syndrome (TSS), which is often caused by Staphylococcus aureus or Streptococcus pyogenes.
Answer Analysis:
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A. Clindamycin: Correct answer.
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Clindamycin is effective against Staphylococcus aureus (including MRSA) and Streptococcus pyogenes. It’s commonly added in cases where toxic shock syndrome is suspected, as it inhibits toxin production and provides coverage for resistant organisms.
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B. Vancomycin:
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Vancomycin is also effective against MRSA, but it’s often added in combination with clindamycin to treat toxic shock syndrome or severe infections with resistant organisms. However, in this case, clindamycin alone may suffice, especially since it also inhibits toxin production.
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C. Benzylpenicillin:
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Benzylpenicillin covers Group A Streptococcus (GAS) and pneumococci, but it wouldn’t provide adequate coverage for MRSA or Staphylococcus aureus (including in cases of toxic shock syndrome). It’s not the best choice in this scenario.
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D. Rifampicin:
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Rifampicin is primarily used in combination therapy for specific infections like tuberculosis, but it is not typically used alone in severe sepsis cases. It’s not the first-line option for the suspected infection in this scenario.
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E. Gentamicin:
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Gentamicin is an aminoglycoside that provides coverage for Gram-negative bacteria but doesn’t offer good coverage for MRSA or Staphylococcus aureus in this case. It’s not the best choice for this clinical presentation.
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Correct Answer: A. Clindamycin
Rationale: The child with disseminated chickenpox, fever, hypotension, and signs of shock requires broad-spectrum antibiotic coverage, including for MRSA and Streptococcus pyogenes. Clindamycin is added in suspected cases of toxic shock syndrome to inhibit bacterial toxin production and provide MRSA coverage.

MRCPCH Exam Preparation Guide: High-Yield Topics and Revision Tips
MRCPCH exam preparation guide: The MRCPCH (Membership of the Royal College of Paediatrics and Child Health) exam is a key milestone for pediatricians aiming to demonstrate their knowledge and clinical skills. Proper preparation is essential to succeed in both the theory and clinical components. This MRCPCH exam preparation guide provides high-yield topics, practical revision strategies, and tips to help you approach the exam with confidence.
High-Yield Topics for MRCPCH
Focusing on high-yield topics is crucial for efficient revision. Core areas include:
- Neonatology: Prematurity, neonatal resuscitation, congenital anomalies.
- Infectious Diseases: Common pediatric infections, vaccination schedules, sepsis management.
- Cardiology: Congenital heart defects, murmurs, arrhythmias.
- Respiratory Medicine: Asthma, bronchiolitis, cystic fibrosis.
- Gastroenterology & Nutrition: Malabsorption, liver diseases, obesity in children.
Covering these topics thoroughly will give you a strong foundation for both theory and clinical exams.
MRCPCH Revision Tips
Effective revision combines structured planning with active practice. Some strategies include:
- Create a study schedule: Divide your time between theory, clinical cases, and mock exams.
- Use flashcards and notes: Highlight key points for quick recall.
- Practice past papers: Familiarize yourself with exam format and timing.
- Join study groups: Discussing cases with peers can improve retention.
Clinical Exam Cases
The clinical component tests practical skills and bedside reasoning. Common scenarios include fever in a child, respiratory distress, rashes, and growth concerns. Practicing these cases helps develop confident patient assessment and management skills.
Conclusion
This MRCPCH exam preparation guide is designed to streamline your study process and focus on high-yield topics. By following structured revision strategies and practicing clinical scenarios, you can maximize your chances of passing the exam with confidence. Start your preparation early, and use this guide to stay on track and organized.

